|
Herb-drug interactions are drug interactions that occur between herbal medicines and conventional drugs. These types of interactions may be more common than drug-drug interactions because herbal medicines often contain multiple pharmacologically active ingredients, while conventional drugs typically contain only one.〔 Some such interactions are clinically significant, although most herbal remedies are not associated with drug interactions causing serious consequences. Most herb-drug interactions are moderate in severity. The most commonly implicated conventional drugs in herb-drug interactions are warfarin, insulin, aspirin, digoxin, and ticlopidine, due to their narrow therapeutic indices.〔 The most commonly implicated herbs involved in such interactions are those containing St. John’s Wort, magnesium, calcium, iron, or ginkgo.〔 ==Examples== Examples of herb-drug interactions include, but are not limited to: *St. John's wort affects the clearance of numerous drugs, including cyclosporin, SSRI antidepressants, digoxin, indinavir, and phenprocoumon.〔 It may also interact with the anti-cancer drugs irinotecan and imatinib. *Salvia miltiorrhiza may enhance anticoagulation and bleeding among people taking warfarin.〔 *Allium sativum has been found to decrease the plasma concentration of saquinavir, and may cause hypoglycemia when taken with chlorpropamide.〔 *Ginkgo biloba can cause bleeding when combined with warfarin or aspirin.〔 *Concomitant ephedra and caffeine use has been reported to, in rare cases, cause fatalities. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Herb-drug interactions」の詳細全文を読む スポンサード リンク
|